Extreme Elevation of Serum Alpha Fetoprotein in Decompensated Cirrhosis without Hcc: an Ominous Sign-Reference-Cited by-同舟云学术

Extreme Elevation of Serum Alpha Fetoprotein in Decompensated Cirrhosis without Hcc: an Ominous Sign

Published:2007-01 Issue:1 Volume:22 Page:19-23
ISSN:1724-6008
Container-title:The International Journal of Biological Markers
language:en
Short-container-title:Int J Biol Markers

Author:

Senturk H.¹,Cumali R.²

Affiliation:

1. Medicine, Department of Gastroenterology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul - Turkey

2. Fellow in Radiology, Section of Radiodiagnostics, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul - Turkey

Abstract

Three cases of extreme elevation of serum alpha fetoprotein (>10,000 ng/mL) with decompensated cirrhosis without demonstrable hepatocellular carcinoma are reported. While 2 patients died of liver failure, 1 survived after liver transplantation. Extreme elevation of alpha fetoprotein not associated with hepatocellular carcinoma in liver cirrhosis heralds an ominous prognosis necessitating urgent liver transplantation.

Publisher

SAGE Publications

Subject

Cancer Research,Clinical Biochemistry,Oncology,Pathology and Forensic Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/172460080702200103

Reference16 articles.

1. Dramatic Reduction of the α-Fetoprotein Level After Lamivudine Treatment of Patients with Chronic Hepatitis B Virus Infection and Cirrhosis

2. Acute Exacerbation of Hepatitis in Liver Cirrhosis with Very High Levels of alpha-Fetoprotein But No Occurrence of Hepatocellular Carcinoma

3. Specificities of serum α-fetoprotein in HBsAg+ and HBsAg− patients in the diagnosis of hepatocellular carcinoma

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