Surgical Complications in a Hemophilia Patient With Factor VIII Inhibitor and Their Endovascular Management-Reference-Cited by-同舟云学术

Surgical Complications in a Hemophilia Patient With Factor VIII Inhibitor and Their Endovascular Management

Published:2008-04 Issue:2 Volume:42 Page:168-172
ISSN:1538-5744
Container-title:Vascular and Endovascular Surgery
language:en
Short-container-title:Vasc Endovascular Surg

Author:

Sadat Umar¹,Naik Jag²,Hayes Paul D.²

Affiliation:

1. Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge, United Kingdom,

2. Cambridge Vascular Unit, Addenbrooke's Hospital, Cambridge, United Kingdom

Abstract

Hemophilia, an X-linked disorder due to clotting factors VIII or IX deficiency, is associated with recurrent hemorrhage into joints, soft tissue, and organs. Recombinant factor VIII concentrates are available for the treatment of bleeding complications. However, inhibitors to factor VIII develop in 25% to 35% of patients with severe hemophilia A, making the management of bleeding episodes more complex. The treatment of unusual metachronous ruptured aneurysms in a patient with hemophilia A with factor VIII inhibitor is presented, and the outcomes of endovascular and open operations are discussed.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1177/1538574407309319

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