Distal Forearm Arteriovenous Fistula Maturation in Diabetic Hemodialysis Patients

Author:

Tayebi Pouya1ORCID,Dadashi Kosar2,Asgharpour Masoumeh3,Moghadamnia Ali A.4,Gholinia Hemmat5,Bijani Ali6

Affiliation:

1. Department of Vascular and Endovascular Surgery, Rouhani Hospital, Babol University of Medical Science, Babol, Iran

2. Student Research Committee, Babol University of Medical Science, Babol, Iran

3. Department of Nephrology, Rouhani Hospital, Babol University of Medical Science, Babol, Iran

4. Department of Pharmacology and Toxicology, Faculty of Medicine, Babol University of Medical Science, Babol, Iran

5. Health Research Institute, Babol University of Medical Science, Babol, Iran

6. Social Determinant of Health Research Center, Babol University of Medical Science, Babol, Iran

Abstract

Purpose Atherosclerotic disease of the forearm arteries can impede the maturation of distal fistulas in diabetic patients. The goal of this study was to look at the maturity of diabetic hemodialysis patients’ distal forearm (radiocephalic snuffbox or distal forearm) arteriovenous fistulas. Materials and Methods Patients with chronic renal failure who were candidates for distal forearm radiocephalic arteriovenous fistula implantation were evaluated in this cross-sectional study. Patients’ demographic details, underlying disorders, laboratory measurements, vital signs, and information on their surgery were all noted. Patients were checked for fistula development 1 week, 1 month, 2 months, and then monthly until 6 months after surgery. Arteriovenous fistula maturation characterized by optimal blood flow, vessel dilation, and structural adaptations. Results Among 343 patients (56% male, 44% female, mean age: 57.32 ± 12.48 years), hypertension prevailed (81.9%), followed by hyperlipidemia (42.3%) and coronary artery disease history (25.9%). AVFs achieved 58.3% maturation in 64.98 ± 11.05 days; higher BP during creation correlated with successful maturation (17.02 ± 1.46 mmHg vs 13.90 ± 1.93 mmHg, P < .05). No significant statistical difference found in distal forearm arteriovenous fistula maturation between males (57.8%) and females (58.9%) ( P > .005). However, 41.7% of AVFs failed in 18.83 ± 17.89 days. Failed AVFs exhibited lower BP during operation and failure (11.75 ± 1.86 mmHg). Kaplan-Meier analysis depicted maturation probabilities over 90 days post-surgery. Conclusion Diabetes and patient sex did not affect the maturation time of distal forearm AVFs in hemodialysis patients. Increased blood pressure during and after surgery correlated with shorter maturation time.

Funder

Babol University of Medical Sciences

Publisher

SAGE Publications

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