A Rare Case of 7 Simultaneous Arterial Dissections and Review of The Literature

Author:

Amitai Komem Daphna12ORCID,Sukenik Halevy Rivka234,Griton Yigal25,Shnaker Ali26,Levy Yair27,Weissmann Jonathan26,Fajer Simone26

Affiliation:

1. Meir Medical Center, Kfar Saba, Israel

2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

3. Genetics Institute, Meir Medical Center, Kfar Saba, Israel

4. Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel

5. Unit of Interventional Radiology, Meir Medical Center, Kfar Saba, Israel

6. Vascular Surgery Unit, Meir Medical Center, Kfar Saba, Israel

7. Department of Medicine E, Meir Medical Center, Kfar Saba, Israel

Abstract

Objective: Spontaneous multiple artery dissection is a relatively rare phenomenon. Early clinical signs are often nonspecific, making it difficult to diagnose. Case Report: This is a case of a 51-year-old female who presented with spontaneous dissection of 4 visceral arteries, both iliac arteries, and of the right internal carotid artery. The patient underwent urgent successful endovascular repair. Later complications included acute respiratory distress syndrome and pneumonia after massive blood transfusion. She recovered gradually and was discharged after 21 days. Due to this rare presentation, genetic investigation was performed in search of a connective tissue disorder. Results revealed a new COL3A1 subtype mutation. The pathogenicity of this variant remains unclear. Conclusion: We recommend a high index of suspicion for visceral artery dissection in the differential diagnosis for abdominal pain with concurrent uncontrolled hypertension. Early diagnosis and intervention are crucial to reducing the mortality rate.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Surgery

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