Affiliation:
1. Division of Biosurface Technology Biomedical Technology Wing Sree Chitra Tirunal Institute for Medical Sciences and Technology Thiruvananthapuram - 695012, India
Abstract
Different ceramic substances are offered in the market as bone substitute materials. These include monophasic calcium phosphate ceramics of tricalciumphosphate (TCP) or hydroxyapatite (HA), biphasic calcium phosphate ceramics and multiphasic bio-glasses synthetic calcium phosphate cements. Ceramics with appropriate three-dimensional geometry are able to bind and concentrate bone morphogenetic proteins in circulation and may become osteoinductive (capable of osteogenesis) and can be effective carriers of bioactive peptide or bone cell seeds and are therefore potentially useful in tissue engineering and drug delivery. An attempt has been made to review various drug delivery applications of ceramics.
Subject
Biomedical Engineering,Biomaterials
Reference52 articles.
1. New Methods of Drug Delivery
2. 2. Langer, R. (1980). Polymeric Delivery Systems for Controlled Drug Release , Chem. Eng. Commun., 6: 15-48 .
3. Ceramic systems for long-term delivery of chemicals and biologicals
4. 5. Hnatyszyn, J.H., Kossovsky, N., Gelman, A. and Sponsler, E. (1994). Drug Delivery Systems for the Future , PDA J. Pharm. Sci. Technol., 48: 247-254 .
5. Analysis of the biocompatibility of ALCAP ceramics in rat femurs
Cited by
117 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献