Nonclinical Kinetics and Metabolism Studies in Support of the Safety Assessment of Drugs

Author:

Heykants Joseph1,Meuldermans Willem2

Affiliation:

1. Pharmacokinetics, Janssen Research Foundation, Beerse, Belgium

2. Non-clinical Pharmacokinetics, Janssen Research Foundation, Beerse, Belgium

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Public Health, Environmental and Occupational Health,Drug Guides,Pharmacology (nursing)

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Preclinical Formulation Assessment ofNCEs;Innovative Dosage Forms;2019-10-07

2. Applied Pharmacokinetics in Drug Development;Pharmaceutical Development and Regulation;2003-06

3. Considerations in the Design of Toxicokinetic Programs;Toxicologic Pathology;1995-03

4. Are we doing too many animal biodisposition investigations before Phase I studies in man?;European Journal of Drug Metabolism and Pharmacokinetics;1994-09

5. Phase I clinical trials: what is the minimum preclinical package necessary for initiating single-dose studies in man? — a toxicologist’s opinion;The Timing of Toxicological Studies to Support Clinical Trials;1994

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