Evidence for statin therapy in polycystic ovary syndrome

Author:

Sathyapalan Thozhukat1,Atkin Stephen L.2

Affiliation:

1. Michael White Diabetes Centre, 220-236 Anlaby Road, Hull Royal Infirmary, Hull HU3 2JZ, UK,

2. Diabetes, Endocrinology and Metabolism, Hull York Medical School, Hull, UK

Abstract

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women of reproductive age group that is associated with increased cardiovascular risk. In addition to its lipid-lowering effects, statin therapy has shown been shown to have beneficial pleiotropic effects that may contribute to their reduction in cardiovascular morbidity and mortality. In this review, the effect of statins on PCOS is discussed with reference to the underlying potential mechanism of action.

Publisher

SAGE Publications

Subject

Endocrinology, Diabetes and Metabolism

Reference79 articles.

1. Effect of Statin Therapy on C-Reactive Protein Levels

2. Azziz, R. , Ehrmann, D. , Legro, R.S. , Whitcomb, R.W. , Hanley, R. , Fereshetian, A.G. et al. (2001)

3. The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population

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