Practical Assessment of the NBT-PABA Pancreatic Function Test Using High Performance Liquid Chromatography Determination of P-Aminobenzoic Acid in Urine-Reference-Cited by-同舟云学术

Practical Assessment of the NBT-PABA Pancreatic Function Test Using High Performance Liquid Chromatography Determination of P-Aminobenzoic Acid in Urine

Published:1985-11 Issue:6 Volume:22 Page:586-590
ISSN:0004-5632
Container-title:Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
language:en
Short-container-title:Ann Clin Biochem

Author:

Berg J D¹,Chesner I²,Lawson N¹

Affiliation:

1. Department of Clinical Chemistry, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST, UK

2. Departments of Gastroenterology, East Birmingham Hospital, Bordesley Green East, Birmingham B9 5ST, UK

Abstract

A practical method for determining p-aminobenzoic acid in urine by high-performance liquid chromatography has been assessed. The technique is quick, requires no extraction steps and has good precision. Using this method, healthy individuals had a p-aminobenzoic acid excretion index of 94% ±18 (mean±1 SD). Patients with proven, severe chronic exocrine pancreatic dysfunction had index values of <5–25%. Unlike chemical methods available, there were no interferences in any of the urines tested, nor did 12 compounds tested interfere with the analysis.

Publisher

SAGE Publications

Subject

Clinical Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/000456328502200606

Reference15 articles.

1. Indirect Pancreatic Function Tests: Chemical and Radioisotope Methods

2. Preliminary evaluation of a single-day tubeless test of pancreatic function.

3. Prospective comparison of three non-invasive tests for pancreatic disease.

4. Prospective comparison of three non-invasive tests for pancreatic disease.

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