Erythrocyte Fatty Acid Profiles in Patients with Bronchogenic Carcinoma

Author:

Taylor A1,Manche A2,Wilson I2,Watson D2,Pandov H1,Lawson N1

Affiliation:

1. Department of Clinical Chemistry, East Birmingham Hospital, Bordesley Green East, Birmingham, UK

2. Department Regional Thoracic Surgery, East Birmingham Hospital, Bordesley Green East, Birmingham, UK

Abstract

The use of the erythrocyte stearic:oleic acid ratio in the diagnosis and prognosis of bronchogenic carcinoma has been assessed. Although there was a significant difference ( P<0·02) in the erythrocyte stearic:oleic acid ratio between bronchogenic carcinoma patients and healthy adults, the large overlap observed in the two groups rendered the test unsuitable for the diagnosis of malignancy. Furthermore, there was no consistent rise in this ratio after surgical resection, indicating the test to be of little prognostic use. A new explanation for the lower stearic:oleic acid ratios in certain patients has been postulated.

Publisher

SAGE Publications

Subject

Clinical Biochemistry,General Medicine

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