Determination of the Anticonvulsant Drug—Dipropyl Acetate (Epilim) in Human Plasma by Gas Chromatography-Reference-Cited by-同舟云学术

Determination of the Anticonvulsant Drug—Dipropyl Acetate (Epilim) in Human Plasma by Gas Chromatography

Published:1977-01 Issue:1-6 Volume:14 Page:240-242
ISSN:0004-5632
Container-title:Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
language:en
Short-container-title:Ann Clin Biochem

Author:

U-Schulz H.¹,Toseland P. A.¹

Affiliation:

1. Medical Hochschule, Lubeck (G.F.R.) and Department of Clinical Chemistry, Guy's Hospital, London SE1 9RT

Abstract

A relatively simple gas chromatographic procedure is proposed for the analysis of the drug dipropylacetic acid in plasma. The compound is chromatographed, as the free acid after ether extraction. Prior to concentration of the solvent the acid is converted to its potassium salt, then regenerated to the free acid immediately before analysis.

Publisher

SAGE Publications

Subject

Clinical Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/000456327701400164

Reference3 articles.

1. Gas-chromatographic analysis for succinimide anticonvulsants in serum: macro- and micro-scale methods.

2. Determination of lower fatty acids, particularly the anti-epileptic dipropyl-acetic acid, in biological materials by means of micro diffusion and gas chromatography

3. Organic Nitrogen-Selective Detector Used in GasChromatographic Determination of Some Anticonvulsant and Barbiturate Drugs in Plasma and Tissues

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