Screening for Down's Syndrome: The Effect of Test Date on the Detection Rate-Reference-Cited by-同舟云学术

Screening for Down's Syndrome: The Effect of Test Date on the Detection Rate

Published:1998-01 Issue:1 Volume:35 Page:57-61
ISSN:0004-5632
Container-title:Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
language:en
Short-container-title:Ann Clin Biochem

Author:

Dunstan F D J,Nix A B J¹

Affiliation:

1. School of Mathematics, University of Wales, Cardiff, Senghenydd Road, Cardiff CF2 4YH, Wales, UK

Abstract

Screening tests for Down's syndrome are carried out at different gestational ages. Because of fetal loss, crude estimates of their detection rates cannot be directly compared. We present methods for estimating the true detection rates along with their standard errors. This enables a proper statistical comparison of the true detection rates of tests carried out, for example, in different trimesters.

Publisher

SAGE Publications

Subject

Clinical Biochemistry,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/000456329803500106

Reference7 articles.

1. Screening for fetal trisomies by maternal age and fetal nuchal translucency thickness at 10 to 14 weeks of gestation

2. Serum screening for Down's syndrome between 8 and 14 weeks of pregnancy

3. Selective miscarriage of Down's syndrome fetuses in women aged 35 years and older

4. DETECTION RATES AND FALSE POSITIVE RATES FOR DOWN'S SYNDROME SCREENING: HOW PRECISELY CAN THEY BE ESTIMATED AND WHAT FACTORS INFLUENCE THEIR VALUE?

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