Assessing illness-related uncertainty in relapsing-remitting multiple sclerosis: A psychometric analysis of the Mishel Uncertainty of Illness Scale-Reference-Cited by-同舟云学术

Assessing illness-related uncertainty in relapsing-remitting multiple sclerosis: A psychometric analysis of the Mishel Uncertainty of Illness Scale

Published:2024-04 Issue:2 Volume:10 Page:
ISSN:2055-2173
Container-title:Multiple Sclerosis Journal - Experimental, Translational and Clinical
language:en
Short-container-title:Multiple Sclerosis Journal - Experimental, Translational and Clinical

Author:

Sabin Julia¹,Salas Elisa²,Martín-Martínez Jesús³,Candeliere-Merlicco Antonio⁴^ORCID,Barrero Francisco Javier⁵,Alonso Ana⁶^ORCID,Sánchez-Menoyo José Luis⁷,Borrega Laura⁸,Rodríguez-Rodríguez María⁹,Gómez-Gutiérrez Montserrat¹⁰,Eichau Sara¹¹,Hernández-Pérez Miguel Ángel¹²,Calles Carmen¹³,Fernández-Díaz Eva¹⁴,Carmona Olga¹⁵,Orvíz Aida¹⁶,López-Real Ana¹⁷,López-Muñoz Pablo¹⁸,Mendoza Amelia¹⁹,Agüera Eduardo²⁰,Maurino Jorge²^ORCID,Ballesteros Javier²¹

Affiliation:

1. Department of Neurology, Hospital Universitario Puerta de Hierro, Madrid, Spain

2. Medical Department, Roche Farma, Madrid, Spain

3. Department of Neurology, Hospital Universitario Miguel Servet, Zaragoza, Spain

4. Department of Neurology, Hospital Rafael Méndez, Lorca, Spain

5. Department of Neurology, Hospital Clínico Universitario San Cecilio, Granada, Spain

6. Department of Neurology, Hospital Regional Universitario de Málaga, Málaga, Spain

7. Department of Neurology, Hospital de Galdakao-Usansolo, Galdakao, Spain

8. Department of Neurology, Hospital Universitario Fundación Alcorcón, Alcorcón, Spain

9. Department of Neurology, Hospital Universitario Lucus Augusti, Lugo, Spain

10. Department of Neurology, Hospital San Pedro de Alcántara, Cáceres, Spain

11. Department of Neurology, Hospital Universitario Virgen Macarena, Sevilla, Spain

12. Department of Neurology, Hospital Universitario Nuestra Señora de Candelaria, Tenerife, Spain

13. Department of Neurology, Hospital Universitario Son Espases, Palma de Mallorca, Spain

14. Department of Neurology, Hospital Universitario de Albacete, Albacete, Spain

15. Department of Neurology, Fundació Salut Empordà, Figueres, Spain

16. Department of Neurology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain

17. Department of Neurology, Complejo Hospitalario Universitario A Coruña, A Coruña, Spain

18. Department of Neurology, Hospital Arnau de Vilanova, Llíria, Spain

19. Department of Neurology, Complejo Asistencial de Segovia, Segovia, Spain

20. Department of Neurology, Hospital Universitario Reina Sofía, Córdoba, Spain

21. Department of Neurosciences, University of Basque Country (UPV/EHU), CIBERSAM, Leioa, Spain

Abstract

A multicenter study involving 204 adults with relapsing-remitting multiple sclerosis (RRMS) assessed the dimensionality and item characteristics of the Mishel-Uncertainty of Illness Scale (MUIS), a generic self-assessment tool. Mokken analysis identified two dimensions in the MUIS with an appropriate item and overall scale scalability after excluding nonclassifiable items. A refined 12-item MUIS, employing a grade response model, effectively discriminated uncertainty levels among RRMS patients (likelihood ratio test p-value = .03). These findings suggest the potential value of the 12-item MUIS as a reliable measure for assessing uncertainty associated with the course of illness in RRMS.

Funder

Roche Farma Spain

Publisher

SAGE Publications

Link

https://journals.sagepub.com/doi/pdf/10.1177/20552173241247680

Reference11 articles.

1. An initial validation of the Italian Mishel Uncertainty Illness Scale (MUIS) for relapsing remitting multiple sclerosis patients

2. Disease Progression in Multiple Sclerosis: A Literature Review Exploring Patient Perspectives

3. Illness perceptions and outcome in multiple sclerosis: A systematic review of the literature

4. Development and Validation of Fear of Relapse Scale for Relapsing-Remitting Multiple Sclerosis: Understanding Stressors in Patients

5. Facing the Unknown: Fear of Progression Could Be a Relevant Psychological Risk Factor for Depressive Mood States among Patients with Multiple Sclerosis