Affiliation:
1. Division of Dermatology, Department of Medicine, University of Louisville School of Medicine, Louisville, Kentucky
Abstract
Background: Pyoderma gangrenosum (PG) is an uncommon condition that is associated with a systemic disease in 50% of patients. The condition may be associated with a monoclonal gammopathy, usually of the IgA type. It is rare for PG to be associated with multiple myeloma. Observations: We report the case of an 83-year-old man with PG associated with an IgA myeloma. The myeloma was discovered after the diagnosis of PG had been made. This is the 22nd case of multiple myeloma associated with PG, and only the 14th case of PG with an IgA myeloma. Conclusions: We should be aware of the potential association of multiple myeloma with PG, and consider doing a serum protein electrophoresis in the evaluation of patients with PG.
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5 articles.
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1. Pyoderma gangrenosum in hematologic malignancies: A systematic review;Journal of the American Academy of Dermatology;2020-06
2. Atypical Pyoderma Gangrenosum Presenting as Paronychia;The American Journal of Medicine;2009-07
3. Pyoderma Gangrenosum: An Update;Rheumatic Disease Clinics of North America;2007-11
4. Pyoderma gangrenosum: an expert commentary;Expert Review of Dermatology;2006-06
5. Neutrophilic dermatoses;Dermatologic Clinics;2002-07