A case report of sinonasal glomangiopericytoma: An important reminder to always collect specimen

Author:

Nichol Ariadne A.1ORCID,Bernard Benjamin J.2,Gilani Sapideh2ORCID

Affiliation:

1. University of California, San Diego School of Medicine, La Jolla, CA, USA

2. Department of Otolaryngology, University of California, San Diego School of Medicine, San Diego, CA, USA

Abstract

Objectives To present a case report of sinonasal glomangiopericytoma (GPC) in a female patient in her thirties and to highlight the importance of collecting pathology specimens even in routine sinus surgery cases. Methods A case report detailing the diagnosis of GPC in a female in her thirties, including her initial presentation, treatment, and follow-up, along with a brief review of the literature. Results Pathology of the collected specimen revealed sinonasal GPC along with chronic rhinosinusitis. Immunohistochemistry was positive for SMA, beta-catenin, and cyclin D1; and negative for STAT6, ERG, pankeratin, SOX10, and S100. Conclusion This diagnosis expands the knowledge around the demographic profile of GPC patients. GPC should be included in the differential diagnosis of sinonasal masses, even in younger patients. The case highlights the importance of collecting the entire pathology specimen in all cases, even of ones that seem routine and benign.

Publisher

SAGE Publications

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