1. From the Department of Intensive Care, Department of Clinical Epidemiology and Biostatistics, Laboratory of Experimental Intensive Care and Anesthesiology, and Department Cardiothoracic Surgery, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands; the Laboratory for Experimental and Clinical Immunology, Sanquin Research at CLB, Amsterdam, The Netherlands; and the Department of Intensive Care, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands