1. Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
2. Department of Gastrointestinal Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
3. Department of Anorectal Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
4. School of Life Sciences, Zhengzhou University, Zhengzhou, Henan, China
5. Key Laboratory for Tumor Immunology and Biotherapy of Henan Province, Zhengzhou, Henan, China
6. Department of Oncology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China