Differences in Composition of Cell-attachment Sialoproteins between Dentin and Bone-Reference-Cited by-同舟云学术

Differences in Composition of Cell-attachment Sialoproteins between Dentin and Bone

Published:1993-08 Issue:8 Volume:72 Page:1222-1226
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Fujisawa R.¹,Butler W.T.²,Brunn J.C.²,Zhou H.Y.¹,Kuboki Y.¹

Affiliation:

1. Department of Biochemistry, School of Dentistry, Hokkaido University, Sapporo, Japan 060

2. Department of Biological Chemistry, University of Texas Health Science Center at Houston, Dental Branch, Houston, Texas 77030-3402

Abstract

Matrices of dentin and bone were compared with respect to the content of cell-attachment sialoproteins. The levels of two sialoproteins, osteopontin (OPN) and bone sialoprotein (BSP), were determined in dentin and bone by immunochemical procedures. Polyclonal antibodies against bovine BSP and an antibody against the amino-terminal decapeptide of rat OPN were used. The relative levels of OPN and BSP in dentin were less than one-tenth of the levels in bone. The differences between dentin and bone levels of OPN and BSP were thus larger than those for osteonectin or bone Gla protein in the two tissues. The scarcity of the cell-attachment proteins in dentin may reflect the metabolic inactivity of dentin.

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/00220345930720081001

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4. Localization of bone sialoprotein (BSP) expression to sites of mineralized tissue formation in fetal rat tissues by In Situ hybridization

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