A Theoretical Study of in vivo Lesion Repair Using a Controlled-release Device-Reference-Cited by-同舟云学术

A Theoretical Study of in vivo Lesion Repair Using a Controlled-release Device

Published:1986-09 Issue:9 Volume:65 Page:1169-1172
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Greene W.M.¹,Newbrun E.²

Affiliation:

1. Department of Chemical Engineering, University of California, Berkeley, California 94720

2. Division of Oral Biology, Department of Stomatology, University of California, San Francisco, California 94143-0512

Abstract

A theoretical model of lesion remineralization predicts that in vivo caries repair can be effected in a five-day period by means of a controlled- and sustained-release device containing calcium, phosphate, and fluoride. The calculations detail an 80% repair before the remineralization process stops. However, the fluoridated hydroxyapatite formed is calculated to be about 20% more resistant to future attack than is hydroxyapatite, making effective repair complete. Optimal flux (W) conditions for repair of 100 μm lesions are WCa = 1.0 x 10-6 kglm2s, stoichiometric phosphate, and WF = 2.0 × 10-9 kg/ m2s.

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/00220345860650091101

Reference18 articles.

1. Mechanism of Dental Caries

2. Arends, J. and Gelhard, T.B.F.M. (1982): In vivo Remineralization of Human Enamel. In: Demineralization and Remineralization of the Teeth, S. A. Leach and W. M. Edgar, Eds. Oxford: IRL Press Ltd., pp. 1-16.

3. Tooth enamel remineralization

4. The growth of crystals and the equilibrium structure of their surfaces

5. A simple model for remineralization of subsurface lesions in tooth enamel

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