Evidence of Intact Histatins in the in vivo Acquired Enamel Pellicle-Reference-Cited by-同舟云学术

Evidence of Intact Histatins in the in vivo Acquired Enamel Pellicle

Published:2010-03-29 Issue:6 Volume:89 Page:626-630
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Siqueira W.L.¹,Margolis H.C.²,Helmerhorst E.J.³,Mendes F.M.⁴,Oppenheim F.G.³

Affiliation:

1. Schulich Dentistry and Department of Biochemistry, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON, Canada

2. Department of Biomineralization, The Forsyth Institute, Boston, MA, USA

3. Department of Periodontology and Oral Biology, Boston University Henry M. Goldman School of Dental Medicine, Boston University, 700 Albany Street, CABR, Suite W-201, Boston, MA 02118, USA

4. Department of Pediatric Dentistry, Faculty of Dentistry, University of São Paulo, Brazil

Abstract

Understanding the composition and function of the acquired enamel pellicle (AEP) has been a major goal in oral biology. The aim of this study was to test the hypothesis that intact histatins are part of the in vivo AEP and that histatins after adsorption to HA have effects on in vitro enamel demineralization. This is the first study demonstrating the presence of intact histatins in vivo in the AEP. The in vitro experiments show that all naturally occurring histatins in the AEP have the potential to provide some level of protection against acid injury.

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/0022034510363384

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