Hereditary Basis of Caries Resistance in Rats

Author:

Chai C.K.1,Hunt H.R.1,Hoppert C.A.1,Rosen S.1

Affiliation:

1. The Jackson Laboratory, Bar Harbor, Maine, Michigan State University, East Lansing, Michigan, Ohio State University, Columbus, Ohio

Abstract

Lines of rats susceptible and resistant to dental caries were produced through 25 and 19 generations of breeding, respectively. Differences in mean caries time between the two lines were found to be as great as more than 500 days in some late generations. Heritability estimates yielded values of 0.40 and 0.62.

Publisher

SAGE Publications

Subject

General Dentistry

Reference26 articles.

1. Inheritance of Susceptibility to Caries in Albino Rats (Mus Norvegicus)

2. Hunt, H.R.; Hoppert, C.A., and Rosen, S.: Genetic Factors in Experimental Rat Caries, in Advances in Experimental Caries Research, AAAS, p. 66, 1955.

3. Microbiologic Differences in the Oral Cavities of the Hunt-Hoppert Caries-Resistant and Caries-Susceptible Rats

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