Affiliation:
1. Department of Periodontology, Temple University School of Dentistry, Philadelphia, Pennsylvania 19140
Abstract
An in vitro system was used to study the detoxifying potential of H2O2 on bacterial endotoxin. L929 fibroblasts were exposed to H202-treated and -untreated endotoxin. Growth and viability assays were made at 24, 48, 72, and 96 h. The cultures exposed to H202-treated endotoxin showed a normal growth rate, whereas the cultures exposed to untreated endotoxin displayed a substantial reduction in growth. Implications are presented as to the potential role of H202 in the pathogenesis and treatment of periodontal disease.
Cited by
10 articles.
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