Degenerative Changes in Masseter Muscle Following Injection of Lidocaine : A Histoehemical Study

Author:

Dolwick M.F.1,Bush F.M.1,Seibel H.R.1,Burke G.W.1

Affiliation:

1. Departments of Oral and Maxillofacial Surgery, Restorative Dentistry and Anatomy, Virginia Commonwealth University, Richmond, Virginia 23298, USA

Abstract

Changes in suceinic dehydrogenase, adenosine triphosphatase, and phosphorylase activities occurred in masseter muscle by 15 minutes following injeetion of 2% lidocaine. Abolishment of phosphorylase activity suggested an effect on the sarcoplasmic retieulum. Increased staining for succinic dehydrogenase and adenosine triphosphatase activities suggested damage to mitochondria and myofibrils, respectively. Leucine aminopeptidase and glucose-6-phosphate dehydrogenase activities appeared in macrophages.

Publisher

SAGE Publications

Subject

General Dentistry

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