The Effects of Parathyroid Hormone, Calcitonin, and Vitamin D Metabolites on Calcium Transport in the Secretory Rat Enamel Organ

Author:

Bawden J.W.1,Deaton T.G.1,Crenshaw M.A.1

Affiliation:

1. The Dental Research Center and the Department of Pedodontics, University of North Carolina, Chapel Hill, North Carolina 27514

Abstract

The effects of parathyroid hormone (PTH), calcitonin (CT), 1,25(OH)2D3, and 24,25(OH) 2D3 on calcium transport through the secretory stage enamel organ were studied on developing rat molars in vitro. 24,25(OH)2D 3 increased 45Ca uptake by the explants. 24,25(OH)2 D3 plus PTH further enhanced 45Ca uptake and resulted in an increase in net calcium uptake by the developing enamel.

Publisher

SAGE Publications

Subject

General Dentistry

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