Effects of Some Staining Agents on Dentin Apposition in Young Rabbits

Author:

Yen Peter K-J.1,Shaw James H.1,Hong Yu-Ching1

Affiliation:

1. Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA

Abstract

Alizarin red S, trypan blue, chlortetracycline, and 45Ca were administered to young rabbits that received multiple injections of lead acetate as marker. Inhibiting effects of these agents on dentin apposition were studied. No evidence of toxicity of chlortetracycline or 45Ca was detected. Alizarin at 100 mg/kg reduced the rate of dentin apposition, and 150 mg/kg caused severe retardation. Trypan blue at 50 to 100 mglkg showed no adverse effects, but 350 mglkg arrested dentinogenesis completely.

Publisher

SAGE Publications

Subject

General Dentistry

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1. Changes in Mineral Content, Mineral Deposition and Vascular Supply of the Mandible After Osteotomy;Scandinavian Journal of Plastic and Reconstructive Surgery;1988-01

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4. Age determination of the African lion (Panthera leo);Journal of Zoology;1978-05

5. Remodeling of Cancellous Bone in Young Monkeys;Journal of Dental Research;1978-02

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