BASIC BIOLOGICAL SCIENCES Dentin Permeability: Changes Produced by Iontophoresis

Author:

Pashley D.H.1,Livingston M.J.1,Outhwaite W.C.1

Affiliation:

1. Departments of Oral Biology, Restorative Dentistry and Physiology, Medical College of Georgia, Augusta, Georgia 30902, USA

Abstract

Iontophoretic currents (0-1.0 mA) were applied to dentin disks prepared from human third molars. A negative electrode increased 125I-permeation 10X, while a positive electrode increased 14C-lidocaine 8X. Iontophoresis appears promising as a method to increase the permeation of dentin by ionized substances of therapeutic interest.

Publisher

SAGE Publications

Subject

General Dentistry

Reference13 articles.

1. Sturridge, E.: Dental Electro-Therapeutics, Philadelphia, Lea and Febiger, pp 219-30, 1918.

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