Studies on Hemolytic Activity of Bisphenol A Diglycidyl Methacrylate (BIS-GMA)

Author:

Fujisawa S.1,Imai Y.1,Fujisawa 1,Kojima K.1,Fujisawa 1,Masuhara E.1

Affiliation:

1. School of Dentistry Tokyo Medical and Dental University, Yushima Bunkyo-ku, Tokyo 113, Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Surugadai, Kanda, Chiyoda-ku Tokyo 101, Japan

Abstract

To clarify the high hemolytic activity of BIS-GMA, the molar concentration producing 50% hemolysis (H 50) and the partition coefficient in-octanol-water were determined using BIS-GMA and various types of methacrylates. It is suggested that the strong hemolytic potency of BIS-GMA is due to the high hydrophobic nature of the compound.

Publisher

SAGE Publications

Subject

General Dentistry

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