Feulgen Microspectrophotometry of Oral Cancer and Leukoplakia

Author:

Doyle John L.1,Manhold John H.1

Affiliation:

1. Department of General and Oral Pathology, New Jersey Dental School, College of Medicine and Dentistry, Jersey City, New Jersey 07304, USA

Abstract

Feulgen microspectrophotometry was performed using the two wavelength method on 33 lesions and showed that five of ten carcinomas and 12 of 16 leukoplakias had diploid cell lines. This correlates well with similar findings in cervical cancer and dysplasia suggesting that changes in nuclear deoxyribonucleic acid content occur quite early in the evolution of cancer.

Publisher

SAGE Publications

Subject

General Dentistry

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