Changes of Serum Alkaline Phosphatase Following Mandibular Osteotomy in the Rat-Reference-Cited by-同舟云学术

Changes of Serum Alkaline Phosphatase Following Mandibular Osteotomy in the Rat

Published:1987-06 Issue:6 Volume:66 Page:1195-1198
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Nilsson L.P.¹,Granström G.²

Affiliation:

1. Laboratory of Oral Biology, Department of Histology, P.O. Box 33031, 400 33 Gothenburg, Sweden

2. Laboratory of Oral Biology, Department of Histology, P.O. Box 33031, 400 33 Gothenburg, Sweden, Department of Oto-, Rhino-, Laryngology, University of Gothenburg, Sweden

Abstract

Activity of alkaline phosphatase in serum (S-ALP) was characterized and compared with that of non-specific alkaline phosphatase (APase) of hard-tissue origin in the rat. The enzyme was characterized bio-chemically, and optimal incubation procedures were determined. S-ALP levels were determined before and after mandibular osteotomy combined with different degrees of periosteal reflections. Separation of S-ALP isoenzymes by isoelectric focusing revealed four major bands. A marked decrease of S-ALP activity was seen after osteotomy, and all isoenzymes were affected similarly. After treatment with hyperbaric oxygen, a smaller decrease in S-ALP was seen. S-ALP could be used as a marker for hard-tissue turn-over after surgical procedures.

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/00220345870660062001

Reference28 articles.

1. A METHOD FOR THE RAPID DETERMINATION OF ALKALINE PHOSPHATASE WITH FIVE CUBIC MILLIMETERS OF SERUM

2. Isoelectric focusing of serum alkaline phosphatase isoenzymes

3. Commission on Biochemical Nomenclature (1972 ): In: Enzyme Nomenclature, New York: American Elsevier (1973), pp. 26-27.

4. Isoenzymes of Human Alkaline Phosphatase

5. Properties of alkaline phosphatases from cellular cementum of rat molars

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