Inductive Materials for Regenerative Engineering-Reference-Cited by-同舟云学术

Inductive Materials for Regenerative Engineering

Published:2021-04-27 Issue:10 Volume:100 Page:1011-1019
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Hosseini F.S.¹²³⁴,Nair L.S.¹²³⁵⁶,Laurencin C.T.¹²³⁵⁶

Affiliation:

1. Connecticut Convergence Institute for Translation in Regenerative Engineering, University of Connecticut Health, Farmington, CT, USA

2. Raymond and Beverly Sackler Center for Biological, Physical and Engineering Sciences, University of Connecticut Health, Farmington, CT, USA

3. Department of Orthopedic Surgery, University of Connecticut Health, Farmington, CT, USA

4. Department of Skeletal Biology and Regeneration, UConn Health, Farmington, CT, USA

5. Department of Biomedical Engineering, University of Connecticut, Storrs, CT, USA

6. Department of Materials Science and Engineering, University of Connecticut, Storrs, CT, USA

Abstract

Regenerative engineering has pioneered several novel biomaterials to treat critical-sized bone injuries. However, despite significant improvement in synthetic materials research, some limitations still exist. The constraints correlated with the current grafting methods signify a treatment paradigm shift to osteoinductive regenerative engineering approaches. Because of their intrinsic potential, inductive biomaterials may represent alternative approaches to treating critical bone injuries. Osteoinductive scaffolds stimulate stem cell differentiation into the osteoblastic lineage, enhancing bone regeneration. Inductive biomaterials comprise polymers, calcium phosphate ceramics, metals, and graphene family materials. This review will assess the cellular behavior toward properties of inductive materials.

Funder

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/00220345211010436

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