Enzymatic Sulfation of Glycosphingolipids in Rat Parotid Salivary Glands-Reference-Cited by-同舟云学术

Enzymatic Sulfation of Glycosphingolipids in Rat Parotid Salivary Glands

Published:1983-10 Issue:10 Volume:62 Page:1026-1030
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Zdebska E.¹,Liau Y.H.¹,Slomiany A.¹,Slomiany B.L.¹

Affiliation:

1. Gastroenterology Research Laboratory, Department of Medicine, New York Medical College, Research Center, Metropolitan Hospital, New York, New York 10029

Abstract

The results of this study demonstrate that sulfatoglycosphingolipids of rat parotid salivary glands consist of galactosylceramide and lactosylceramide sulfates. The enzyme activity which catalyzes the formation of these compounds in vitro via transfer of sulfate from 3'-phosphoadenosine-5'-phosphosulfate to galactosyl- and lactosylceramide is located in the microsomal fraction of parotid glands. This sulfotransferase exhibits its optimum activity at pH 6.8 and requires the presence of Triton X-100, Mg2 +, and F1-.

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/00220345830620100201

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