Affiliation:
1. Dental and Research Services, Veterans Administration Medical Center, West Roxbury, Massachusetts and Harvard School of Dental Medicine, Boston, Massachusetts 02115
Abstract
The biocompatibility of two implant materials, vitallium and poly-methyl methacrylate (PMMA), was evaluated in an animal model in which bone formation and resorption are independent of each other. Neither material accelerated resorption, but formation was inhibited 12% by vitallium and 38% by PMMA. When three PMMA preparations varying in monomer content were tested, the data exhibited a dose-response relation, suggesting that inhibition of bone formation was due to the presence of residual monomer.
Cited by
16 articles.
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