Perineural Invasion in Head and Neck Cancer-Reference-Cited by-同舟云学术

Perineural Invasion in Head and Neck Cancer

Published:2018-02-14 Issue:7 Volume:97 Page:742-750
ISSN:0022-0345
Container-title:Journal of Dental Research
language:en
Short-container-title:J Dent Res

Author:

Schmitd L.B.¹,Scanlon C.S.¹,D’Silva N.J.¹²

Affiliation:

1. Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA

2. Department of Pathology, Medical School, University of Michigan, Ann Arbor, MI, USA

Abstract

Perineural invasion (PNI) is a mechanism of tumor dissemination that can provide a challenge to tumor eradication and that is correlated with poor survival. Squamous cell carcinoma, the most common type of head and neck cancer, has a high prevalence of PNI. This review provides an overview of clinical studies on the outcomes and factors associated with PNI in head and neck cancer and on findings on cancer-nerve crosstalk.

Funder

National Institute of Dental and Craniofacial Research

Publisher

SAGE Publications

Subject

General Dentistry

Link

http://journals.sagepub.com/doi/pdf/10.1177/0022034518756297

Reference60 articles.

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5. Mechanisms of Perineural Invasion

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