Collagenolytic Activity of Crevicular Fluid from Pericoronal Gingival Flaps

Author:

Golub Lorne M.1,Kennett Stanley1,Mcewan Helen1,Curran John B.1,Ramamurthy N.S.1

Affiliation:

1. School of Dental Medicine, State University of New York at Stony Brook, Stony Brook, New York 11790, USA, Faculty of Dentistry, University of Manitoba, Winnipeg, Canada

Abstract

Collagenolytic activity was seen in fluids from the mandibular pericoronal gingival flap. Based on the response of this activity to sodium thiocyanate, and on the disc gel electrophoretic pattern of the collagen breakdown products, the collagenase appeared to be of tissue rather than of bacterial origin. Moreover, this activity seemed to parallel the collagenase activity and the breakdown of collagen in the adjacent gingival tissue, and thus, may be of diagnostic importance.

Publisher

SAGE Publications

Subject

General Dentistry

Reference19 articles.

1. Collagen metabolism in pericoronitis

2. Piez, K.A.: Chemistry of Collagen and Elastin and Biosynthesis of Covalent Crosslinks , in Engle, A., and Larsson, T. (eds) : Ageing of Connective and Skeletal Tissue , Stockholm : Nordisk, Bokhand, Forlag, 1969, pp 15-32.

3. Resistance to collagenase: A characteristic of collagen fibrils cross-linked by formaldehyde

4. Cimasoni, G.: The Crevicular Fluid, in Myers, H.M. (ed) : Monographs in Oral Science, Vol 3, Basel: S. Karger , 1974, pp 64-100.

5. COLLAGENOLYTIC ACTIVITY IN AMPHIBIAN TISSUES: A TISSUE CULTURE ASSAY

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