Development of Caries in the Hunt-Hoppert Caries-Susceptible and Caries-Resistant Rats Under Different Experimental Conditions

Author:

Larson Rachel H.1,Keyes Paul H.1,Goss Bette Joan1

Affiliation:

1. US Department of Health, Education, and Welfare, Public Health Service, National Institute of Dental Research, National Institutes of Health, Bethesda, Maryland

Abstract

Rats of both Hunt-Hoppert lines, originally designated as caries-susceptible (Ca-S) and caries-resistant (Ca-R) lines, were highly susceptible to caries when subjected to a combination of diet and microflora that provided a challenge to the resistance of all surfaces of the teeth. Strain differences were indicated by the predominance of sulcal lesions in the Ca-S line and smooth-surface lesions in the Ca-R line.

Publisher

SAGE Publications

Subject

General Dentistry

Reference23 articles.

1. Inheritance of Susceptibility to Caries in Albino Rats (Mus Norvegicus)

2. Stephan, R.M., and Harris, M.R. "Location of Experimental Caries on Different Tooth Surfaces in the Norway Rat," in R. F. Sognnaes (ed.), Aduances in Experimental Caries Research, Washington, DC: American Association for the Advancement of Science, 1955, pp 47-65.

3. Dental Caries in the Molar Teeth of Rats

4. Hereditary limitations of the infectious and transmissible nature of experimental dental caries

5. Caries development in rats of different ages with controlled flora

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