Affiliation:
1. Department of Pharmacology, Faculty of Stomatology, University of Belgrade, Dr.
Subotica 8, Belgrade, Yugoslavia
Abstract
The effects of obidoxime, a pyridinium oxime, on the cholinesterase activity and acetylcholine content of the submandibular glands of rats poisoned with armin, an organophosphorus anticholinesterase agent, were studied. The results indicate that obidoxime-induced reactivation of phosphorylated cholinesterase can suppress completely the increase in the concentration of acetylcholine that develops within the submandibular gland after administration of armin alone.
Cited by
1 articles.
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