The Effects of Tetracyclines on Teeth and Bones

Abstract

SYNOPSIS IN INTERLINGUA LE EFFECTO DE TETRACYCLINAS SUPER DENTES E OSSOS.—Esseva ideate quatro experimentos con rattos visante a studiar le effectos macroscopic e histologic del 4 homologos tetracyclinic, i.e., chlortetracyclina (CTC), demethylchlortetracyclina (DCTC), tetracyclina (TC), e oxytetracyclina (OTC). Adulte rattos mascule del linea Wistar esseva tractate durante 21 dies con le tetracyclinas per via oral al recommendate doses therapeutic adjustate al peso del animales. Juvene adulte rattos feminin recipeva le varie tetracyclinas durante le curso de un pregnantia. Rattos feminin in stato lactifere recipeva le homologos durante 21 dies post le parturition. Rattos de etates dislactatori recipeva 39 diurne doses therapeutic del tetracyclinas a partir del vinti-prime die de lor vitas.