Brain Contusions: The Time Sequence of the Histological Changes

Abstract

Microscopical sections from 65 cases with brain contusions of known age were studied in order to obtain histological data for age determination of the lesions. The earliest histological alterations were observed within one hour after the lesion and they changed in an orderly fashion over the following hours, days and weeks (Figure 1). It is concluded that the age of brain contusions can be determined with reasonable accuracy from routinely stained histological sections.