Preoperative Opioid Use Predicts Poorer Outcomes of Total Ankle Arthroplasty and Hindfoot Fusions

Author:

Newton William1,Hoch Caroline2ORCID,Chen Caroline1,Scott Daniel J.1ORCID,Gross Christopher E.1

Affiliation:

1. Department of Orthopaedics & Physical Medicine, Medical University of South Carolina, Charleston, South Carolina

2. Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Abstract

Background This study aimed to determine the impact of preoperative opioid use on outcomes of patients undergoing ankle or hindfoot arthrodesis, or total ankle arthroplasty (TAA). Methods We conducted a retrospective review of 190 patients undergoing an ankle or hindfoot arthrodesis (n=122) or TAA (n=68) between December 2015 and September 2020 with a single fellowship-trained orthopaedic foot and ankle surgeon at an academic medical center. Data collected included demographics, medical comorbidities, treatment history, complications and reoperation rates, patient-reported outcome measures (PROMs) (eg, Foot and Ankle Outcome Score [FAOS]), and opioid use. Results Patients with preoperative opioid use were more likely to continue usage at 90 (r = 0.931, P < .001) and 180 (r = 0.940, P < .001) days postoperatively. For the entire cohort, complication and reoperation rates were 48.9% and 13.2%, respectively. While preoperative opioid use groups did not differ in the overall complication rate, users had significantly more infections (user = 12.5%, nonuser = 3.3%; P = .036) and reoperations (user = 22.5%, nonuser = 10.7%; P = .049). When analyzing postoperative opioid prescriptions, there were many significant correlations with preoperative PROMs, mainly FAOS, such that increased postoperative opioid use was associated with worse subjective outcomes. Conclusion Preoperative opioid users are more likely to continue postoperative opioid use, experience infections, and undergo reoperations. Level of Evidence: Level III: Retrospective cohort study

Publisher

SAGE Publications

Subject

Orthopedics and Sports Medicine,Podiatry,Surgery

Reference25 articles.

1. Adverse effects of chronic opioid therapy for chronic musculoskeletal pain

2. American Academy of Orthopaedic Surgeons. Treatment of Osteoarthritis of the Knee–2nd Edition Evidence-based Clinical Practice Guideline. https://www.aaos.org/globalassets/quality-and-practice-resources/osteoarthritis-of-the-knee/osteoarthritis-of-the-knee-2nd-editiion-clinical-practice-guideline.pdf. Published May 18, 2013. Accessed March 18, 2023.

3. American Academy of Orthopaedic Surgeons. Management of Osteoarthritis of the hip: evidence-based clinical practice guideline. Date unknown. http://www.orthoguidelines.org/topic?id=1021. Accessed March 18, 2023.

4. Characteristics of Opioid Prescriptions in 2009

5. Chronic Opioid Use Prior to Total Knee Arthroplasty

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