Eosinophilic leukemia in three African pygmy hedgehogs (Atelerix albiventris) and validation of Luna stain-Reference-Cited by-同舟云学术

Eosinophilic leukemia in three African pygmy hedgehogs (Atelerix albiventris) and validation of Luna stain

Published:2017-01-24 Issue:2 Volume:29 Page:217-223
ISSN:1040-6387
Container-title:Journal of Veterinary Diagnostic Investigation
language:en
Short-container-title:J VET Diagn Invest

Author:

Martínez-Jiménez David¹²³⁴⁵,Garner Bridget¹²³⁴⁵,Coutermarsh-Ott Sheryl¹²³⁴⁵,Burrell Caitlin¹²³⁴⁵,Clark Sabrina¹²³⁴⁵,Nabity Mary¹²³⁴⁵,Díaz-Delgado Josué¹²³⁴⁵,Rodrigues-Hoffmann Aline¹²³⁴⁵,Zaks Karen¹²³⁴⁵,Proença Laila¹²³⁴⁵,Divers Stephen¹²³⁴⁵,Saba Corey¹²³⁴⁵,Cazzini Paola¹²³⁴⁵

Affiliation:

1. Loving Hands Animal Clinic (Martínez-Jiménez), Alpharetta, GA

2. Departments of Pathology (Cazzini, Coutermarsh-Ott, Garner) and Small Animal Medicine and Surgery (Proença, Divers, Saba), College of Veterinary Medicine, University of Georgia, Athens, GA

3. Departments of Small Animal Clinical Sciences (Burrell) and Veterinary Pathobiology (Clark, Nabity, Díaz-Delgado, Rodrigues-Hoffmann), College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX; and

4. Department of Microbiology, Immunology and Pathology (Zaks), College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO. Current affiliations: Cumming Veterinary Clinic, Cumming, GA (Martínez-Jiménez)

5. Easter Bush Pathology, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Edinburgh, UK (Cazzini); and Smithsonian Conservation Biology Institute, Front Royal, VA (Burrell)

Abstract

Neoplasia is usually encountered in the African pygmy hedgehog at a mean age of 3.5 y, and malignancy is common. Myelogenous leukemias are rarely reported in hedgehogs. We describe 3 cases of eosinophilic leukemia in adult, middle-aged (mean age: 2.3 y) hedgehogs, for which prognosis appears grave. In 1 case, attempted treatment was unsuccessful, and in all 3 cases, the disease course was rapid and all died soon after diagnosis. Blood smear evaluation, along with complete blood count, was critical in making the diagnosis in all cases. Luna stain was validated and used to better visualize eosinophils in cytologic and histologic sections. Electron microscopy confirmed the presence of specific granules in hedgehog eosinophils.

Publisher

SAGE Publications

Subject

General Veterinary

Link

http://journals.sagepub.com/doi/pdf/10.1177/1040638716687603

Reference21 articles.

1. Chronic eosinophilic leukemia in a cat: cytochemical and immunophenotypical features

2. Anaplastic Astrocytoma in the Spinal Cord of an African Pygmy Hedgehog (Atelerix albiventris)

3. Comparison of three staining methods to identify eosinophils in formalin-fixed canine skin

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