The Detection of Antibodies to the Glycoprotein X Antigen of Pseudorabies Virus-Reference-Cited by-同舟云学术

The Detection of Antibodies to the Glycoprotein X Antigen of Pseudorabies Virus

Published:1990-01 Issue:1 Volume:2 Page:24-28
ISSN:1040-6387
Container-title:Journal of Veterinary Diagnostic Investigation
language:en
Short-container-title:J VET Diagn Invest

Author:

Cook Donald¹,Hill Howard¹,Snyder Michael²,McMahon Philip²,Kinker David¹

Affiliation:

1. Veterinary Diagnostic Laboratory, Iowa State University, Ames, IA 50010

2. IDEXX Corp., 100 Fore Street, Portland, ME 04101

Abstract

The persistence of antibodies to glycoprotein X (gpX) in the serum of pigs experimentally infected with pseudorabies virus (PRV) was determined using an anti-gpX enzyme-linked immunosorbent assay (ELISA). Antibodies to gpX were detected for at least 365 days postchallenge in nonvaccinated pigs. Previous sensitization of pigs by vaccination with S/PRV had no apparent effect on the antibody response of pigs to gpX postchallenge. In determining previous exposure of pigs to PRV strains containing the gpX gene, the anti-gpX ELISA was highly specific, but its sensitivity was lower than the standard serological procedures currently used for detecting PRV antibodies.

Publisher

SAGE Publications

Subject

General Veterinary

Link

http://journals.sagepub.com/doi/pdf/10.1177/104063879000200105

Reference11 articles.

1. Intranasal vaccination of pigs against Aujeszky’s disease: comparison with inactivated vaccines in pigs with low maternal antibody titres

2. Aujeszky's disease: new vaccines and diagnostics

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1. Development and preliminary application of gE enzyme-linked immunosorbent assay for detection of the antibody to gE protein ofPseudorabies virusin pigs;Chinese Journal of Agricultural Biotechnology;2005-08

2. Evaluation of serological tests for the detection of pseudorabies gE antibodies during early infection;Veterinary Microbiology;1997-04

3. Differentiation between glycoprotein III gene-deleted vaccine and wild-type strains of pseudorabies virus by polymerase chain reaction (PCR);Journal of Virological Methods;1995-02

4. Factors associated with circulation of Aujeszky's disease virus in fattening herds of an intensively vaccinated area of Northern Germany;Preventive Veterinary Medicine;1994-07

5. Evaluation of Serological Pseudorabies Tests for the Detection of Antibodies during Early Infection;Journal of Veterinary Diagnostic Investigation;1993-10