Malignant Peripheral Nerve Sheath Tumor of Tongue: A Rare Tumor of Oral Cavity

Author:

Yadav Ajay1,Goyal Jaishree1,Yadav Dinesh2,Sethi Neha3,Vijayvargiya Maneesh3

Affiliation:

1. Department of Medical Oncology, Mahatma Gandhi University of Medical Science and Technology, Jaipur, Rajasthan, India

2. Department of Surgical Oncology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India

3. Department of Oncopathology, Mahatma Gandhi Medical College and Hospital, Jaipur, Rajasthan, India

Abstract

Malignant peripheral nerve sheath tumor (MPNST) is a rare tumor of oral cavity. Tongue is an extremely rare site for MPNST. We present a rare case of MPNST of tongue in a 34-year-old male. Presentation remains same as carcinoma of tongue but histopathology and immunohistochemistry help to establish the diagnosis. Biopsy of lesion was suggestive of malignant spindle cell neoplasm. On immunohistochemical examination, tumor cells were immunopositive for vimentin and S100 and SMA. Patient underwent surgery followed by adjuvant radiotherapy in order to reduce the risk of recurrence.

Publisher

SAGE Publications

Subject

General Earth and Planetary Sciences,General Environmental Science

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