Discrepancy in the Thrombolytic Effect of UK Between Angiographic and Circulatory Evaluations-Reference-Cited by-同舟云学术

Discrepancy in the Thrombolytic Effect of UK Between Angiographic and Circulatory Evaluations

Published:1984-08 Issue:8 Volume:35 Page:523-527
ISSN:0003-3197
Container-title:Angiology
language:en
Short-container-title:Angiology

Author:

Matsuo Osamu¹,Mihara Hisashi¹,Motomatsu Kenichi²

Affiliation:

1. Department of Physiology, Kinki University School of Medicine, Sayama, Osaka, Japan

2. Department of Physiology and Anesthesiology, Miyazaki Medical College, Miyazaki, Japan

Abstract

A clinical case in which angiographic and circulatory evaluations of the thrombolytic effect of urokinase (UK) were not correlated, is described. Circu latory improvement distal to the thrombosis was recognized on the basis of a rise in skin temperature and increased palpability of the pulse at the distal artery. However, angiography revealed the development of thrombosis. This discrepancy may have arisen from the hypotensive action of UK preparations due to increased flow in the collateral circulation. The significance of angiogra phy in providing direct evidence for assessing the thrombolytic effect of UK is emphasized.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/000331978403500810

Reference14 articles.

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5. Isolation and characterization of alpha2-plasmin inhibitor from human plasma. A novel proteinase inhibitor which inhibits activator-induced clot lysis.