Hemorheologic Factors in the Postacute Phase of Ischemic Stroke

Author:

Ciuffetti Giovanni1,Mercuri Michele1,Parnetti Lucilla1,Lupattelli Graziana1,Senin Umberto1

Affiliation:

1. 2nd Department of Internal Medicine, Gerontologic and Geriatric Chair, Faculty of Medicine, University of Perugia, Perugia, Italy

Abstract

Clinical and hemorheologic data were recorded in a homogeneous group of 72 patients (age range sixty-one to seventy years), suffering from ischemic stroke with an onset of less than eight hours, confirmed clinically and by com puterized tomography. A quantitative neurologic analysis and the following he morheologic parameters were monitored for twenty weeks following the acute episode: fibrinogen, total proteins, albumin, hematocrit, leukocyte and platelet counts, whole blood filterability (WBF), red blood cell deformability (RBCD), and blood plasma, and serum viscosity. The results show a significant decrease in hematocrit values parallel to the clinical neurologic improvement and a sig nificant increase in RBCD in the patients with the better clinical recovery. These data confirm the role of hemorheologic parameters in the clinical follow-up of cerebrovascular disorders.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

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