Acetylcholine-Induced Myocardial Ischemia Without Epicardial Coronary Artery Spasm: A Possible Vasospasm of Small Coronary Arteries

Acetylcholine-Induced Myocardial Ischemia Without Epicardial Coronary Artery Spasm: A Possible Vasospasm of Small Coronary Arteries—A Case Report

Published:1993-10 Issue:10 Volume:44 Page:811-815
ISSN:0003-3197
Container-title:Angiology
language:en
Short-container-title:Angiology

Author:

Sekiya Michihito¹,Okayama Hideki¹,Suzuki Makoto¹,Kobayashi Takamasa¹,Matsuoka Hiroshi¹,Sumimoto Takumi¹,Hamada Mareomi¹,Hiwada Kunio¹

Affiliation:

1. The Second Department of Internal Medicine, Ehime University School of Medicine, Onsengun, Ehime, Japan

Abstract

Small-vessel vasospasm has been speculated upon as a possible cause of chest pain in patients with normal-appearing coronary angiograms. In this report, a patient who experienced typical chest pain during acetylcholine testing, which caused ST segment elevation without epicardial coronary spasm, is presented. This finding suggests that small-vessel vasospasm may be involved in the induction of myocardial ischemia in patients with normal epicardial coronary arteries.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/000331979304401008

Reference15 articles.

1. Angina pectoris in patients with normal and abnormal coronary arteriograms

2. Paradox of Normal Selective Coronary Arteriograms in Patients Considered to Have Unmistakable Coronary Heart Disease

3. Spectrum of exercise thallium-201 myocardial perfusion imaging in patients with chest pain and normal coronary angiograms

4. Reduced coronary dilatory capacity and ultrastructural changes of the myocardium in patients with angina pectoris but normal coronary arteriograms.

5. Angina caused by reduced vasodilator reserve of the small coronary arteries

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