Prognostic Significance of Prevalent and Incident Atrial Fibrillation Among Patients Hospitalized with Acute Coronary Syndrome

Author:

Hersi Ahmad1,Alhabib Khalid F.1,Alsheikh-Ali Alawi A.2,Sulaiman Kadhim3,Alfaleh Hussam F.1,Alsaif Shukri4,Mahmeed Wael Al-2,Asaad Nidal5,Haitham Amin6,Al-Motarreb Ahmed7,Suwaidi Jassim5,Shehab Abdullah8

Affiliation:

1. Department of Cardiac Sciences, College of Medicine, King Saud University, Riyadh, Saudi Arabia

2. Department of Cardiac Sciences, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates

3. Cardiology Department, Royal Hospital, Muscat, Oman

4. Cardiology Department, Saud Al-Babtain Cardiac Center, Dammam, Saudi Arabia

5. Department of Cardiology and Cardiovascular Surgery, Hamad Medical Corporation (HMC), Doha, Qatar

6. Cardiology Department, Mohammed Bin Khalifa Cardiac Center, Manama, Bahrain

7. Department of Medicine, Faculty of Medicine, Sana’a University, Sana’a Yemen

8. Department of Medicine, The Faculty of Medicine & Health Sciences (FMHS), UAE University, Abu Dhabi, United Arab Emirates

Abstract

There is a paucity of data on atrial fibrillation (AF) complicating acute coronary syndrome (ACS) in Arabian Gulf countries. Thus, we assessed the incidence of AF in patients with ACS in these countries and examined the associated in-hospital, 30-day, and 1-year adverse outcomes. The population comprised 7930 patients enrolled in the second Gulf Registry of Acute Coronary Events (Gulf RACE-2). Of 7930 patients with ACS, 217 (2.7%) had AF. Compared with patients without AF, patients with AF were less likely to be male (65.9 vs 79.1%) and were older (mean age 64.6 vs 56.6 years). Compared with patients without AF, in-hospital, 30-day, and 1-year mortality were significantly higher in patients with any AF (odds ratio [OR]: 2.7, 2.2, 1.9, respectively; P < .001) and in patients with new-onset AF (OR: 5.2, 3.9, 3.1, respectively; P < .001. In conclusion, AF in patients with ACS was associated with significantly higher short- and long-term mortality.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

Reference19 articles.

1. Trends in Atrial Fibrillation Complicating Acute Myocardial Infarction

2. Comparison of outcomes of patients with acute coronary syndromes with and without atrial fibrillation

3. New-onset atrial fibrillation and acute coronary syndrome

4. Atrial fibrillation in acute myocardial infarction: a systematic review of the incidence, clinical features and prognostic implications

5. American College of Cardiology key data elements and definitions for measuring the clinical management and outcomes of patients with acute coronary syndromes31This document was approved by the American College of Cardiology Board of Trustees in November 2001.32When citing this document, the American College of Cardiology would appreciate the following citation format: Cannon CP, Battler A, Brindis RG, Cox JL, Ellis SG, Every NR, Flaherty JT, Harrington RA, Krumholz HM, Simoons ML, Van de Werf FJJ, Weintraub WS. ACC Key Elements and Data Definitions for Measuring the Clinical Management and Outcomes of Patients with Acute Coronrary Syndromes: a report of the American College of Cardiology Task Force on Clinical Data Standards (Acute Coronary Syndromes Writing Committee). J Am Coll Cardiol 2001;38:2114–30.33This document is available on the World Wide Web site of the American College of Cardiology (www.acc.org). Reprints of this document may be purchased for $5.00 each by calling 1-800-253-4636 or by writing to the American College of Cardiology, Educational Services, 9111 Old Georgetown Road, Bethesda, Maryland 20814-1699. © 2001 by the American College of Cardiology

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