Association Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease Complexity in Patients With Acute Coronary Syndrome

Author:

Ağaç Mustafa Tarık1,Korkmaz Levent1,Çavuşoğlu Gökhan2,Karadeniz Ayşe Gül2,Ağaç Süret3,Bektas Hüseyin1,Erkan Hakan1,Varol Mustafa Oguz1,Vatan Mehmet Bulent4,Acar Zeydin1,Menteşe Ümit5,Çelik Şükrü1

Affiliation:

1. Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey

2. Department of Radiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey

3. Department of Biochemistry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey

4. Department of Cardiology, Faculty of Medicine, Sakarya University, Sakarya, Turkey

5. Department of Cardiovascular Surgery, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, Turkey

Abstract

Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with acute coronary syndrome (ACS). We assessed the association between NAFLD and SYNTAX Score (SS) in patients with ACS. Eighty consecutive patients with ACS were enrolled. Patients were evaluated using ultrasound to detect NAFLD and hepatosteatosis stage. The prevalence of NAFLD was 81.2%; median SS was 15. The SS was significantly higher in patients with NAFLD (18 ± 8 vs. 11 ± 5, P = .001). Univariate analysis showed that the stage of NAFLD correlated with SS ( r = .6, P < .001). In multivariate binary logistic analysis, increased age (odds ratio [OR], 1.05; 95% confidence interval [CI],1.00-1.10) and presence of NAFLD (OR, 13.20; 95% CI, 2.52-69.15) were independent factors associated with supramedian SS. In conclusion, among patients with ACS, those with NAFLD have more complex CAD as assessed by SS.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

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