Beta-Blocker-Induced Psoriasis: A Rare Side Effect

Author:

Birhan Yilmaz Mehmet1,Turhan Hasan1,Akin Yesim1,Kisacik Halil L.1,Korkmaz Sule1

Affiliation:

1. Yuksek Ihtisas Hospital, Cardiology Clinic, Ankara, Turkey

Abstract

Beta blockers are one of the oral agents shown to decrease cardiovascular morbidity and mortality rates in randomized, controlled trials, and hence, they are widely used for the management of many cardiovascular situations. In terms of side effects there are 3 major modes of action: (1) contraction of smooth muscles, particularly of bronchi with nonselective agents; (2) exaggerated cardiac effects; and (3) central nervous system effects. There are also some rare side effects of beta blockers, some of which are unpredictable, but the others are related to mode of action at the cellular level. Beta-blocking agents may cause psoriaform eruptions and worsen existing psoriasis. Psoriasis may be an inconvenient side effect of beta blockade. Herein, we report a case of beta-blocker-induced psoriasis.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

Reference6 articles.

1. Frishman WH, Sonnenblick EH: Beta-adrenergic blocking drugs and calcium channel blockers. In: Hurst's The Heart, ed 9, ed. by Alexander RW, Schlant RC, Fuster V. New York: McGraw-Hill , 1998, pp 1583-1618.

2. Opie LH, Sonnenblick EH, Frishman WH, et al: Beta-blocking agents. In: Drugs for the Heart, ed. 4, ed. by Opie LH. Philadelphia: WB Saunders Company, 1995, pp 1-29.

3. Skin Reactions to Beta-blockers

4. Generalized Pustular Psoriasis Provoked by Propranolol

5. Lymphocyte blast transformation

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