Endovascular Treatment of Transplant Renal Artery Stenosis: Evaluation of Postoperative Outcomes and Risk Factors for Recurrence

Author:

Roustan François-René12,Lareyre Fabien23ORCID,Bentellis Imad1,Haider Romain1,Torrino Stéphanie2,Sedat Jacques4,Albano Laetitia5,Jean-Baptiste Elixène23,Raffort Juliette26,Durand Matthieu1

Affiliation:

1. Department of Urology, University Hospital of Nice, Nice, France

2. Université Côte d’Azur, CHU, Inserm, C3M, Nice, France

3. Department of Vascular Surgery, University Hospital of Nice, Nice, France

4. Department of Interventional Radiology, University Hospital of Nice, Nice, France

5. Department of Nephrology, University Hospital of Nice, Nice, France

6. Clinical Chemistry Laboratory, University Hospital of Nice, Nice, France

Abstract

Angioplasty with or without stenting has become a well-established procedure to treat transplant renal artery stenosis (TRAS). We evaluated our experience on postoperative outcomes following the intervention and identified potential predictive factors of TRAS recurrence. Consecutive patients who underwent endovascular treatment of TRAS were retrospectively reviewed. The study end points were the technical success, 30-day postoperative complications, and the estimated glomerular filtration rate (eGFR). Thirty-two patients underwent endovascular treatment for TRAS. The technical success rate was 96.6%. Complications were observed for 7 (21.9%) patients: 4 had a dissection, 2 a pseudoaneurysm, and 1 (3.1%) patient developed an acute pulmonary edema. The mean eGFR significantly increased at 7 days, 3 months, and 6 months postintervention (43.1, 44.9, and 44.3 vs 33.9 mL/min/1.73 m2 preoperatively, P < .05). The TRAS recurrence was observed in 7 (21.9%) patients. These patients had significantly higher preoperative peak systolic velocity and systolic rise time (5 vs 4 m/s, P = .0383 and 103 vs 80 milliseconds, P = .0148, respectively). Endovascular treatment of TRAS is associated with high technical success and significant improvement in renal function. Further studies are required to confirm predictive factors of TRAS recurrence following endovascular treatment.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

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