The Effect of β-Blockade on Leg Blood Flow in Hypertensive Patients with Intermittent Claudication-Reference-Cited by-同舟云学术

The Effect of β-Blockade on Leg Blood Flow in Hypertensive Patients with Intermittent Claudication

Published:1986-03 Issue:3 Volume:37 Page:149-153
ISSN:0003-3197
Container-title:Angiology
language:en
Short-container-title:Angiology

Author:

Boström Per-Åke¹,Janzon Lars²,Ohlsson Ola³,Westergren Anita⁴

Affiliation:

1. From the Department of Internal Medicine, Lund University, Malmö General Hospital, Malmö, Sweden

2. From the Department of Surgery, Lund University, Malmö General Hospital, Malmö, Sweden

3. Department of Internal Medicine, Kristianstad Hospital, Kristianstad, Sweden

4. From the Department of Clinical Physiology, Lund University, Malmö General Hospital, Malmö, Sweden

Abstract

The present study was designed to assess the short-term effects of β-blocking antihypertensive treatment on leg blood flow in patients with peripheral artery disease. Seven patients with intermittent claudication were randomly allocated to treatment with atenolol 100 mg or pindolol 10 mg. Patients switched therapy after one month of treatment. Venous occlusion plethysmography on the calves was used to assess the effects on leg blood flow after one and two months of treatment. The average 10% reduction of the systolic and diastolic blood pres sures was not associated with any reduction of blood flow at rest. There was on average 3.4 ml reduction of peak flow which had no influence on the painfree or total walking distance.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/000331978603700302

Reference14 articles.

1. Five-Year Findings of the Hypertension Detection and Follow-up Program

2. Intermittent claudication complicating beta-blockade.

3. Intermittent Claudication and Hypertension. Ankle Pressure and Walking Distance in Patients with Well-Treated and Non-Treated Hypertension

4. Effect of a new beta-adrenergic blocking agent, ICI 66o82, on exercise haemodynamics and airway resistance in angina pectoris.

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