Relationship Between Mean Platelet Volume and Atherosclerosis in Young Patients With ST Elevation Myocardial Infarction

Author:

Ozkan Bugra1,Uysal Onur Kadir2,Duran Mustafa2,Sahin Durmus Yildiray3,Elbasan Zafer3,Tekin Kamuran3,Cagliyan Caglar Emre3,Cayli Murat3

Affiliation:

1. Department of Cardiology, Burdur Bucak State Hospital, Burdur, Turkey

2. Department of Cardiology, Kayseri Education and Research Hospital, Kayseri, Turkey

3. Department of Cardiology, Adana Numune Education and Research Hospital, Adana, Turkey

Abstract

Increased mean platelet volume (MPV) is associated with poor clinical outcome in patients with acute coronary syndrome. We evaluated the predictive role of MPV in young patients with acute myocardial infarction (AMI). This study includes 373 patients who presented to our hospital with AMI (group 1: 134 young patients, males aged <45 years and females aged <55 years; group 2: 239 older patients) and 141 adults with normal coronary angiography as a control group (group 3). In group 1, the levels of MPV and hemoglobin were higher than that in groups 2 and 3. In group 1, blood urea nitrogen levels were lower than that in groups 2 and 3 and creatinine levels were lower than that in group 2. After multivariate analysis, MPV and age were independent predictors of AMI in young patients.

Publisher

SAGE Publications

Subject

Cardiology and Cardiovascular Medicine

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